Vivek Jeyakumar

Vivek Jeyakumar, PhD MSc

Post-Doc - Zentrum für Regenerative Medizin

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Projekte (Auszug Forschungs­datenbank)

Regulating functional meniscus tissue regeneration by 3D-bioprinted complex geometrically precise hybrid scaffolds

Developmental tissue engineering model of endochondral ossification for bone regeneration

Cell-based therapies for regenerating bone

Publikationen (Auszug Forschungs­datenbank)

Bauer, C.; Moser, L.B.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2022). Increased Chondroprotective Effect of Combining Hyaluronic Acid with a Glucocorticoid Compared to Separate Administration on Cytokine-Treated Osteoarthritic Chondrocytes in a 2D Culture. Biomedicines, 10: doi:10.3390/biomedicines10071733

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Klestil, T.; Franek, F.; Nehrer, S. (2021). Biotribological Tests of Osteochondral Grafts after Treatment with Pro-Inflammatory Cytokines. Cartilage, Epub ahead of print: 10.1177/1947603521994900

Jeyakumar, V.; Amraish, N.; Niculescu-Morzsa, E.; Bauer, C.; Pahr, D.; Nehrer, S. (2021). Decellularized Cartilage Extracellular Matrix Incorporated Silk Fibroin Hybrid Scaffolds for Endochondral Ossification Mediated Bone Regeneration. International Journal of Molecular Sciences, 22(8): doi.org/10.3390/ijms22084055

Moser, L; Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Nehrer, S. (2021). Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro. International Journal of Molecular Sciences, 22: 10.3390/ijms222111503

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Tóth, I.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Effect of osteochondral graft orientation in a biotribological test system. Journal of Orthopaedic Research, Mar, 37(3): 10.1002/jor.24236

Bauer, C.; Stotter, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Simlinger, B.; Rodriguez Ripoll, M.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Concentration-Dependent Effects of Cobalt and Chromium Ions on Osteoarthritic Chondrocytes. Cartilage, Epub ahead of print: 10.1177/1947603519889389

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2019). Redifferentiation of Articular Chondrocytes by Hyperacute Serum and Platelet Rich Plasma in Collagen Type I Hydrogels. International Journal of Molecular Sciences, Jan 14;20(2): 10.3390/ijms20020316

Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2017). Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits-a pilot study. Journal of Experimental Orthopaedics, 4(1):14: 14

Jeyakumar, V.; Halbwirth, F.; Niculescu-Morzsa, E.; Bauer, C.; Zwickl, H.; Kern, D.; Nehrer, S. (2017). Chondrogenic Gene Expression Differences between Chondrocytes from Osteoarthritic and Non-OA Trauma Joints in a 3D Collagen Type I Hydrogel. Cartilage, 8(2): 191-198

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2017). Platelet-Rich Plasma Supports Proliferation and Redifferentiation of Chondrocytes during In Vitro Expansion. Frontiers in Bioengineering and Biotechnology, 5:75: doi: 10.3389/fbioe.2017.00075

Bauer, C.; Niculescu-Morzsa, E.; Höller, S.; Hornof, M.; Kern, D.; Jeyakumar, V.; Nehrer, S. (2016). Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo. Journal of Orthopaedic Research, 34(S1)

Bauer, C.; Niculescu-Morzsa, E.; Jeyakumar, V.; Kern, D.; Späth, S.S.; Nehrer, S. (2016). Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages. Journal of Inflammation (London, England): 31

Bauer, C.; Niculescu-Morzsa, E.; Jeyakumar, V.; Kern, D.; Späth, S.S.; Nehrer, S. (2016). Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages. Journal of Inflammation, 13(1): 31

Jeyakumar, V.; Halbwirth, F.; Niculescu-Morzsa, E.; Bauer, C.; Zwickl, H.; Kern, D.; Nehrer, S. (2016). Chondrogenic Gene Expression Differences between Chondrocytes from Osteoarthritic and Non-OA Trauma Joints in a 3D Collagen Type I Hydrogel. Cartilage

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Kern, D.; Lacza, Z.; Nehrer, S. (2016). Effects of human serum from platelet-rich fibrin (SPRF) and platelet-rich plasma (PRP) on the chondrogenic differentiation potential of osteoarthritic chondrocytes. European Cells and Materials, 31(Suppl. 1): 43

Zwickl, H.; Niculescu-Morzsa, E.; Halbwirth, F.; Bauer, C.; Jeyakumar, V.; Reutterer, A.; Berger, M.; Nehrer, S. (2016). Correlation Analysis of SOX9, -5, and -6 as well as COL2A1 and Aggrecan Gene Expression of Collagen I Implant-Derived and Osteoarthritic Chondrocytes. Cartilage, 7(2): 185-192

Vorträge (Auszug Forschungs­datenbank)

Biotribological tests of osteochondral grafts after treatment with pro-inflammatory cytokines

International Conference on Biotribology, 27.04.2021

Silk Fibroin Reinforced Decellularized Cartilage ECM Hybrid Scaffolds for Endochondral Bone Regeneration

Frontiers in Silk science and technology, Trento, Italy, 12.06.2019

Cartilage Derived Extracellular Matrix Incorporated Silk Fibroin Hybrid Scaffolds for Endochondral Ossification Mediated Bone Tissue Regeneration

TERMIS 2019 EU, Rhodes, Greece, 23.05.2019

Interchange in culture supplementation from human serum to platelet-rich plasma achieves both proliferation and matrix turnover of chondrocytes

5th TERMIS WORLD CONGRESS, Kyoto, Japan, 02.09.2018

Enhancing the redifferentiation potential of OA chondrocytes in collagen type I hydrogels by supplementing platelet-derivatives

8th World Congress of Biomechanics, Dublin, Ireland, 08.07.2018

Differential Effects of Platelet-Derived Products on ECM turnover by OA Chondrocytes in Collagen Hydrogels

GOTS-Jahreskongress 2017, At Berlin, Germany, 18.06.2017

Differential effects of platelet-derived products on ECM turnover by OA chondrocytes in collagen hydrogels

TERMIS European Chapter Meeting 2017, Davos, Switzerland, 18.06.2017

Effects of Platelet-Derived Products on ECM turnover by OA Chondrocytes in Collagen Hydrogels

ORS 2017, Annual Meeting of the Orthopaedic Research Society, At San Diego, California, United States, 18.03.2017

Chondrogenic differentiation potential of osteoarthritic chondrocytes under human serum from platelet-rich fibrin (SPRF) and platelet-rich plasma (PRP)

TERMIS-EU congress 2016, European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society, At Uppsala, Sweden, 18.06.2016

Effects of human serum from platelet-rich fibrin (SPRF) and platelet-rich plasma (PRP) on the chondrogenic differentiation potential of osteoarthritic chondrocytes

Annual Meeting of the Orthopaedic Research Society 2016, 18.03.2016

Donor age variation in human serum derived-platelet rich fibrin influences the proliferation rate of osteoarthritic chondrocytes

32. Jahrestagung der Österreichischen Gesellschaft für Orthopädie und orthopädische Chirurgie, 31.10.2015

Chondrocytes from osteoarthritic and healthy joints differ in chondrogenic gene expression on a 3D collagen type I hydrogel

World Conference on Regenerative Medicine, Leipzig, Germany, 21.10.2015

Donor age variation in human serum derived-platelet rich fibrin influences the proliferation rate of osteoarthritic chondrocytes

Österreichische Gesellschaft für Orthopädie congress 2015, Vienna, Austria, 18.10.2015

Chondrocytes from osteoarthritic and healthy joints differ in chondrogenic gene expression on a 3D collagen type I hydrogel

World Conference on Regenerative Medicine, At Leipzig, Germany, 18.10.2015

Human Platelet-Rich Plasma Enhances Proliferation and Synthesizes sGAG Production of OA Chondrocytes in a Tissue-Engineered Construct

4th TERMIS World Congress 2015, Boston, 08.09.2015

Human Platelet-rich Plasma enhances proliferation and synthesizes sGAG production of OA chondrocytes in a tissue-engineered construct

4th TERMIS World Congress, Boston, USA, 08.09.2015