Vivek Jeyakumar, PhD MSc

Center for Regenerative Medicine

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Projects (Extract Research Database)

Regulating functional meniscus tissue regeneration by 3D-bioprinted complex geometrically precise hybrid scaffolds

Developmental tissue engineering model of endochondral ossification for bone regeneration

Cell-based therapies for regenerating bone

Publications (Extract Research Database)

Bauer, C.; Moser, L.B.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2022). Increased Chondroprotective Effect of Combining Hyaluronic Acid with a Glucocorticoid Compared to Separate Administration on Cytokine-Treated Osteoarthritic Chondrocytes in a 2D Culture. Biomedicines, 10: doi:10.3390/biomedicines10071733

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Klestil, T.; Franek, F.; Nehrer, S. (2021). Biotribological Tests of Osteochondral Grafts after Treatment with Pro-Inflammatory Cytokines. Cartilage, Epub ahead of print: 10.1177/1947603521994900

Jeyakumar, V.; Amraish, N.; Niculescu-Morzsa, E.; Bauer, C.; Pahr, D.; Nehrer, S. (2021). Decellularized Cartilage Extracellular Matrix Incorporated Silk Fibroin Hybrid Scaffolds for Endochondral Ossification Mediated Bone Regeneration. International Journal of Molecular Sciences, 22(8): doi.org/10.3390/ijms22084055

Moser, L; Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Nehrer, S. (2021). Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro. International Journal of Molecular Sciences, 22: 10.3390/ijms222111503

Bauer, C.; Göcerler, H.; Niculescu-Morzsa, E.; Jeyakumar, V.; Stotter, C.; Tóth, I.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Effect of osteochondral graft orientation in a biotribological test system. Journal of Orthopaedic Research, Mar, 37(3): 10.1002/jor.24236

Bauer, C.; Stotter, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Simlinger, B.; Rodriguez Ripoll, M.; Klestil, T.; Franek, F.; Nehrer, S. (2019). Concentration-Dependent Effects of Cobalt and Chromium Ions on Osteoarthritic Chondrocytes. Cartilage, Epub ahead of print: 10.1177/1947603519889389

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2019). Redifferentiation of Articular Chondrocytes by Hyperacute Serum and Platelet Rich Plasma in Collagen Type I Hydrogels. International Journal of Molecular Sciences, Jan 14;20(2): 10.3390/ijms20020316

Bauer, C.; Jeyakumar, V.; Niculescu-Morzsa, E.; Kern, D.; Nehrer, S. (2017). Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits-a pilot study. Journal of Experimental Orthopaedics, 4(1):14: 14

Jeyakumar, V.; Halbwirth, F.; Niculescu-Morzsa, E.; Bauer, C.; Zwickl, H.; Kern, D.; Nehrer, S. (2017). Chondrogenic Gene Expression Differences between Chondrocytes from Osteoarthritic and Non-OA Trauma Joints in a 3D Collagen Type I Hydrogel. Cartilage, 8(2): 191-198

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Lacza, Z.; Nehrer, S. (2017). Platelet-Rich Plasma Supports Proliferation and Redifferentiation of Chondrocytes during In Vitro Expansion. Frontiers in Bioengineering and Biotechnology, 5:75: doi: 10.3389/fbioe.2017.00075

Bauer, C.; Niculescu-Morzsa, E.; Höller, S.; Hornof, M.; Kern, D.; Jeyakumar, V.; Nehrer, S. (2016). Characterization of cross-linked hyaluronic acid scaffolds in vitro and in vivo. Journal of Orthopaedic Research, 34(S1)

Bauer, C.; Niculescu-Morzsa, E.; Jeyakumar, V.; Kern, D.; Späth, S.S.; Nehrer, S. (2016). Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages. Journal of Inflammation, 13(1): 31

Bauer, C.; Niculescu-Morzsa, E.; Jeyakumar, V.; Kern, D.; Späth, S.S.; Nehrer, S. (2016). Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages. Journal of Inflammation (London, England): 31

Jeyakumar, V.; Halbwirth, F.; Niculescu-Morzsa, E.; Bauer, C.; Zwickl, H.; Kern, D.; Nehrer, S. (2016). Chondrogenic Gene Expression Differences between Chondrocytes from Osteoarthritic and Non-OA Trauma Joints in a 3D Collagen Type I Hydrogel. Cartilage

Jeyakumar, V.; Niculescu-Morzsa, E.; Bauer, C.; Kern, D.; Lacza, Z.; Nehrer, S. (2016). Effects of human serum from platelet-rich fibrin (SPRF) and platelet-rich plasma (PRP) on the chondrogenic differentiation potential of osteoarthritic chondrocytes. European Cells and Materials, 31(Suppl. 1): 43

Zwickl, H.; Niculescu-Morzsa, E.; Halbwirth, F.; Bauer, C.; Jeyakumar, V.; Reutterer, A.; Berger, M.; Nehrer, S. (2016). Correlation Analysis of SOX9, -5, and -6 as well as COL2A1 and Aggrecan Gene Expression of Collagen I Implant-Derived and Osteoarthritic Chondrocytes. Cartilage, 7(2): 185-192

Lectures (Extract Research Database)

Biotribological tests of osteochondral grafts after treatment with pro-inflammatory cytokines

International Conference on Biotribology, 27/04/2021

Silk Fibroin Reinforced Decellularized Cartilage ECM Hybrid Scaffolds for Endochondral Bone Regeneration

Frontiers in Silk science and technology, Trento, Italy, 12/06/2019

Cartilage Derived Extracellular Matrix Incorporated Silk Fibroin Hybrid Scaffolds for Endochondral Ossification Mediated Bone Tissue Regeneration

TERMIS 2019 EU, Rhodes, Greece, 23/05/2019

Interchange in culture supplementation from human serum to platelet-rich plasma achieves both proliferation and matrix turnover of chondrocytes

5th TERMIS WORLD CONGRESS, Kyoto, Japan, 02/09/2018

Enhancing the redifferentiation potential of OA chondrocytes in collagen type I hydrogels by supplementing platelet-derivatives

8th World Congress of Biomechanics, Dublin, Ireland, 08/07/2018

Differential Effects of Platelet-Derived Products on ECM turnover by OA Chondrocytes in Collagen Hydrogels

GOTS-Jahreskongress 2017, At Berlin, Germany, 18/06/2017

Differential effects of platelet-derived products on ECM turnover by OA chondrocytes in collagen hydrogels

TERMIS European Chapter Meeting 2017, Davos, Switzerland, 18/06/2017

Effects of Platelet-Derived Products on ECM turnover by OA Chondrocytes in Collagen Hydrogels

ORS 2017, Annual Meeting of the Orthopaedic Research Society, At San Diego, California, United States, 18/03/2017

Chondrogenic differentiation potential of osteoarthritic chondrocytes under human serum from platelet-rich fibrin (SPRF) and platelet-rich plasma (PRP)

TERMIS-EU congress 2016, European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society, At Uppsala, Sweden, 18/06/2016

Effects of human serum from platelet-rich fibrin (SPRF) and platelet-rich plasma (PRP) on the chondrogenic differentiation potential of osteoarthritic chondrocytes

Annual Meeting of the Orthopaedic Research Society 2016, 18/03/2016

Donor age variation in human serum derived-platelet rich fibrin influences the proliferation rate of osteoarthritic chondrocytes

32. Jahrestagung der Österreichischen Gesellschaft für Orthopädie und orthopädische Chirurgie, 31/10/2015

Chondrocytes from osteoarthritic and healthy joints differ in chondrogenic gene expression on a 3D collagen type I hydrogel

World Conference on Regenerative Medicine, Leipzig, Germany, 21/10/2015

Chondrocytes from osteoarthritic and healthy joints differ in chondrogenic gene expression on a 3D collagen type I hydrogel

World Conference on Regenerative Medicine, At Leipzig, Germany, 18/10/2015

Donor age variation in human serum derived-platelet rich fibrin influences the proliferation rate of osteoarthritic chondrocytes

Österreichische Gesellschaft für Orthopädie congress 2015, Vienna, Austria, 18/10/2015

Human Platelet-rich Plasma enhances proliferation and synthesizes sGAG production of OA chondrocytes in a tissue-engineered construct

4th TERMIS World Congress, Boston, USA, 08/09/2015

Human Platelet-Rich Plasma Enhances Proliferation and Synthesizes sGAG Production of OA Chondrocytes in a Tissue-Engineered Construct

4th TERMIS World Congress 2015, Boston, 08/09/2015