Description

In this project, we will develop advanced methods for the flow cytometric characterization of extracellular vesicles. We will (i) establish novel approaches for the simultaneous detection of surface markers on extracellular vesicles using the MACSPlex technology; (ii) develop flow cytometric methods for the characterization of vesicles in the size range below 200 nm (binding to magnetic beads, fluorescence triggering), (iii) set up a method for the flow cytometric characterization of neutrophil extracellular traps, and (iv) characterize the role of extracellular vesicles in immunomodulation.

Details

Duration 01/01/2021 - 31/12/2022
Funding Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program
Department

Department for Biomedical Research

Center for Biomedical Technology

Principle investigator for the project (University for Continuing Education Krems) Mag. Rene Weiss, PhD

Lectures

Characterization of tissue factor-bearing extracellular vesicles in COVID-19 provides evidence for platelet-monocyte aggregate formation.

ESAO Winter School 2023, 17/02/2023

Characterization of tissue factor-bearing extracellular vesicles in COVID-19

Small New World - Joint Meeting of ASEV & GSEV, 28/10/2022

Yap/Taz Facilitates Extracellular Vesicle Release upon Mechanical Stimulation

48th ESAO Congress, 09/09/2022

Characterization of Tissue Factor-Bearing Extracellular Vesicles in COVID-19

48th ESAO Congress, 08/09/2022

Release of EVs in shock wave therapy depends on the Hippo pathway

ASEV Young Scientists Meeting, 15/10/2021

Extracellular vesicles are associated with C-reactive protein during sepsis

10th Annual Meeting ISEV 2021, 18/05/2021

Extracellular vesicles from activated platelets induce a shift towards proinflammatory monocyte subsets

10th Annual Meeting ISEV 2021, 18/05/2021

Extracellular vesicles from activated platelets induce a shift towards proinflammatory monocyte subsets

12th Annual ÖGMBT Meeting (Infection & Immunity), 26/01/2021

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