Microwave based biosensors with printable surface modifications for point-of-care testing of haemodialysis patients

Description

To allow rapid and label-free biosensing, a cost-efficient and miniaturized biosensor with a simple and direct transducer scheme should be employed. Integrated-optical waveguide devices using evanescent wave sensing are an attractive concept with this respect and have been intensively studied. Another concept that has been attempted only very recently, exploits evanescent waves in the microwave regime, which offers the advantage of low-cost sender and receiver components. In particular, microwave-resonator (MR) based designs are considered as highly promising transducers for the detection of biomolecules. In the last years, high-Q MRs came in focus to design devices with unique electromagnetic properties which are not readily occurring in nature. The research group of Pendry was the first who designed a new class of artificial materials with a continuous change of the electric permittivity and the magnetic permeability from positive to negative values. This class of materials is called metamaterials and can produce interesting new effects (e.g. negative refractive index, a perfect microwave cloak and sophisticated concentrators) which can be used because of their sensitivity for sensing applications. Different sensor designs based on artificial metamaterials and printable surface modifications for label-free biosensing are part of the project. ** This work is partially co-funded by the NÖ Forschungs- und Bildungsges.m.b.H. (NFB) within the Life Science Call. The authors are responsible for the contents of this publication.

Details

Duration 01/01/2015 - 31/12/2017
Funding Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program Life Science Call NFB
Department

Department for Integrated Sensor Systems

Center for Water and Environmental Sensors

Principle investigator for the project (Danube University Krems) Dipl.-Ing. Dr. Martin Brandl
Project members Dipl.-Ing. Lisa-Marie Wagner, BSc

Publications

Brandl, M.; Wagner, L.M. (2018). Microwave Oscillator Design for a SRR Based Biosensor Platform. MDPI Proceedings, 2(13): 865

Wagner, L. M.; Strasser, F.; Melnik, E.; Brandl, M. (2017). Electromagnetic Characterization and Simulation of a Carbonate Buffer System on a Microwave Biosensor. Jean-Paul Viricelle, Christophe Pijolat and Mathilde Rieu, Proceedings, 1(4): doi:10.3390/proceedings1040276, MDPI, Basel

Wagner, L. M. (2017). Development and optimization of a biosensor device based on microwave split-ring resonators. Donau-Universität Krems, TU-Wien, Diplomarbeit

Voglhuber-Brunnmaier, T.; Wagner, L.; Diskusb, C.G.; Jakoby, B.; Brandl, M. (2016). Sensitivity Optimization of Microwave Biosensors. Procedia Engineering, Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 168: 634–637

Wellenzohn, M.; Brandl, M. (2015). A Theoretical Design of a Biosensor Device Based on Split Ring Resonators for Operation in the Microwave Regime. Procedia Engineering, Vol. 120: 865–869

Lectures

Microwave Oscillator Design for a SRR based Biosensor Platform

IEEE Eurosensors 2018 Conference, Graz, Austria, 11/09/2018

Centred gap split ring resonator for high sensitive detection of biomarkers during haemodialysis

MNE2017, 20/09/2017

Electromagnetic Characterization and Simulation of Carbonate Buffer System on a Microwave Biosensor

Eurosensors 2017, 04/09/2017

Optimization of a Biosensor Device based on a microwave Split-Ring Resonator

MNE 2016, 29/09/2016

A microwave split ring resonator (SRR) with hydrogel based biofunctionalization for sensor applications

Biosensors 2016, 26/05/2016

A theoretical design of a biosensor device based on split ring resonators for operation in the microwave regime

XXIX Eurosensors 2015, September 6 to 9, 2015, Freiburg, Germany, 07/09/2015

A biosensor device based on microwave split ring resonators

Jahrestagung der Österreichischen Physikalischen Gesellschaft, 1-4. Sept. Wien, 01/09/2015

Team

Dipl.-Ing. Lisa-Marie Wagner, BSc

Center for Water and Environmental Sensors

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