Projects (Extract Research Database)

Running projects

Systematic literature review to identify effective preventive methods for bloodstream infections (BSI) and other infections, associated with peripheral intravascular catheters (PIVC)

Duration: 01/03/2023–31/08/2023
Principle investigator for the project (University for Continuing Education Krems): Andreea Dobrescu
Funding: andere internationale Organisationen

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Primary Treatment of Confirmed SARS-CoV-2 Infection in Outpatient Settings: Surveillance Searches for Living Guidelines

Duration: 01/07/2022–30/06/2023
Principle investigator for the project (University for Continuing Education Krems): Isolde Sommer
Funding: andere internationale Organisationen

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Nonpharmacological versus Pharmacological Treatments for Major Depressive Disorder: Surveillance Searches for Living Guidelines

Duration: 01/07/2022–30/06/2023
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: andere internationale Organisationen

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Developing rapid review guidance for clinical research

Duration: 01/02/2022–30/06/2024
Principle investigator for the project (University for Continuing Education Krems): Ursula Griebler
Funding: andere internationale Organisationen

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Use of preprint articles in prevention research – a mixed-methods approach

Duration: 01/10/2020–28/02/2023
Principle investigator for the project (University for Continuing Education Krems): Isolde Sommer

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Drug Effectiveness Review Project/Cooperation RTI

Duration: 01/06/2018–30/06/2024
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: andere internationale Organisationen

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Completed projects

WO24-Targeted Immune Modulators - Ulcerative Colitis and Crohn Diseases: Systematic Review Update

Duration: 01/07/2022–30/04/2023
Principle investigator for the project (University for Continuing Education Krems): Andreea Dobrescu
Funding: andere internationale Organisationen

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The Austrian school health system: a status quo assessment

Duration: 01/07/2021–31/12/2022
Principle investigator for the project (University for Continuing Education Krems): Ursula Griebler
Funding: Bund (Ministerien)

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Pharmacological Versus Non-Pharmacological Interventions for the Treatment of Major Depressive Disorder

Duration: 10/06/2020–31/03/2022
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: andere internationale Organisationen

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HT19-04: Depressionen bei Kindern und Jugendlichen: Führt Psychotherapie im Vergleich zu anderen Therapien zu besseren Ergebnissen?

Duration: 01/12/2019–31/08/2021
Principle investigator for the project (University for Continuing Education Krems): Barbara Nußbaumer-Streit
Funding: andere internationale Organisationen

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Systematischer Review Point of Care Ultrasound

Duration: 11/10/2018–31/03/2021
Principle investigator for the project (University for Continuing Education Krems): Gerald Gartlehner
Funding: andere internationale Organisationen

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Cochrane Review Update - Prävention häuslicher Bleibelastung bei Kindern

Duration: 13/03/2020–31/08/2020
Principle investigator for the project (University for Continuing Education Krems): Barbara Nußbaumer-Streit
Funding: andere internationale Organisationen

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Publications (Extract Research Database)

Affengruber, L.; Wagner, G.; Dobrescu, A.; Toromanova, A.; Chapman, A.; Persad, E.; Klerings, I.; Gartlehner, G. (2023). Values and Preferences of Patients With Depressive Disorders Regarding Pharmacologic and Nonpharmacologic Treatments. A Rapid Review. Annals of Internal Medicine, 176(2): 217-223.

Dobrescu, A.; Chapman, A.; Affengruber, L.; Persad, E.; Toromanova, A.; Wagner, G.; Klerings, I.; Emprechtinger, R.; Gartlehner, G. (2023). Cost-Effectiveness of First- and Second-Step Treatment Strategies for Major Depressive Disorder. A Rapid Review. Annals of Internal Medicine, 176(2): 212-216

Gartlehner, G.; Dobrescu, A.; Chapman, A.; Toromanova, A.; Emprechtinger, R.; Persad, E.; Affengruber, L.; Pieh, C.; Klerings, I.; Wagner, G. (2023). Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder. A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians. Annals of Internal Medicine, 176: 196-211

Griebler, U.; Dobrescu, A.; Ledinger, D.; Klingenstein, P.; Sommer, I.; Emprechtinger, R.; Persad, E.; Gadinger, A.; Trivella, M.; Klerings, I.; Nussbaumer-Streit, B. (2023). Evaluation of the interim Cochrane rapid review methods guidance—A mixed-methods study on the understanding of and adherence to the guidance. Research Synthesis Methods, https://doi.org/10.1002/jrsm.1656: 1-12

Affengruber, L.; Dobrescu, A.; Persad, E.; Klerings, I.; Wagner, G.; Sommer, I.; Gartlehner, G. (2022). Characteristics and recovery methods of studies falsely excluded during literature screening-a systematic review. Systematic Reviews, 11: 236

Dobrescu, A.I.; Ebenberger, A.; Harlfinger, J.; Griebler, U.; Klerings, I.; Nussbaumer-Streit, B.; Chapman, A.; Affengruber, L.; Gartlehner, G. (2022). Effectiveness of interventions for the remediation of lead-contaminated soil to prevent or reduce lead exposure - A systematic review. Science of The Total Environment, Volume 806, Part 1: https://doi.org/10.1016/j.scitotenv.2021.150480

Gartlehner, G.; Emprechtinger, R.; Hackl, M.; Jutz, F.L.; Gartlehner, J.E.; Nonninger, J.N.; Klerings, I.; Dobrescu, A.I. (2022). Assessing the magnitude of reporting bias in trials of homeopathy: a cross-sectional study and meta-analysis. BMJ Evidence-Based Medicine, Published Online First: 15 March 2022.: doi: 10.1136/bmjebm-2021-111846

Sommer, I.; Dobrescu, A.; Ledinger, D.; Moser, I.; Thaler, K.; Persad, E.; Fangmeyer, M.; Emprechtinger, R.; Klerings, I.; Gartlehner, G. (2022). Outpatient Treatment of Confirmed COVID-19. A Living, Rapid Review for the American College of Physicians. Annals of Internal Medicine, Online ahead of print.: 1-14

Sommer, I.; Harlfinger, J.; Kien, C.; Klerings, I.; Affengruber, L.; Dobrescu, A.; Griebler, U. (2022). Stakeholders’ perceptions and experiences of factors influencing the commissioning, delivery, and uptake of general health checks: a qualitative evidence synthesis (Protocol). Cochrane Database of Systematic Reviews, Issue 3: Art. No.: CD014796.

Dobrescu, A.; Gartlehner, G.; Wagner, G.; Chapman, A.; Moick, S.; Kahwati, L. (2022). Targeted immune modulators for rheumatoid arthritis and ankylosing spondylitis: update. Center for Evidence-based Policy, Oregon Health & Science University, -: -

Nußbaumer-Streit, B.; Kien, C.; Titscher, V.; Dobrescu, A.; Teufer, B.; Probst, T.; Strohmaier, C.; Stanak, M.; Zechmeister-Koss, I.; Kallab, S. (2022). Depression bei Kindern und Jugendlichen. Führt Psychotherapie im Vergleich zu anderen Therapien zu besseren Ergebnissen? IQWiG-Bericht, Version 1.0: HTA-Nummer HT19-04

Dobrescu, A.; Nussbaumer-Streit, B.; Klerings, I.; Wagner, G.; Persad, E.; Sommer, I.; Herkner, H.; Gartlehner, G. (2021). Restricting evidence syntheses of interventions to English-language publications is a viable methodological shortcut for most medical topics: a systematic review. Journal of Clinical Epidemiology, 137: 209-217

Ewald, H., Klerings, I.; Wagner, G.; Heise, T.L.; Dobrescu, A.I.; Armijo-Olivo, S.; Stratil, J.M.; Lhachimi, S.K.; Mittermayr, T.; Gartlehner, G.; Nussbaumer-Streit, B.; Hemkens, L.G. (2020). Abbreviated and comprehensive literature searches led to identical or very similar effect estimates: a meta-epidemiological study. Journal of Clinical Epidemiology, 128: 1-12

Nussbaumer-Streit, B.; Klerings, I.; Dobrescu, A.I.; Persad, E.; Stevens, A.; Garritty, C.; Kamel, C.; Affengruber, L.; King, V.J.; Gartlehner, G. (2020). Excluding non-English publications from evidence-syntheses did not change conclusions: a meta-epidemiological study. Journal of Clinical Epidemiology, 118: 42-54

Nussbaumer-Streit, B.; Mayr, V.; Dobrescu, A.I.; Chapman, A.; Persad, E.; Klerings, I.; Wagner, G.; Siebert, U.; Christof, C.; Zachariah, C.; Gartlehner, G.; (2020). Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review. Cochrane Database of Systematic Reviews, Issue 4: Art. No.: CD013574.

Nussbaumer-Streit, B.; Mayr, V.; Dobrescu; A.I.; Wagner, G.; Chapman, A.; Pfadenhauer, L.M.; Lohner, S.; Lhachimi, S.K.; Busert, L.K.; Gartlehner, G.; (2020). Household interventions for secondary prevention of domestic lead exposure in children (Review). Cochrane Database of Systematic Reviews, Issue 10: Art. No.: CD006047

Viswanathan, M.; Kahwati, L.; Jahn,B.; Giger, K.; Dobrescu, A.I.; Hill, C.; Klerings, I.; Meixner, J.; Persad, E.; Teufer, B.; Gartlehner, G. (2020). Universal screening for SARS-CoV-2 infection:a rapid review. Cochrane Database of Systematic Reviews, Issue9.: Art.No.:CD013718.

Gartlehner, G.; Wagner, G.; Lux, L.; Affengruber, L.; Dobrescu, A.; Kaminski-Hartenthaler, A.; Viswanathan, M. (2019). Assessing the accuracy of machine-assisted abstract screening with DistillerAI: a user study. Systematic Reviews, 8:277: https://doi.org/10.1186/s13643-019-1221-3

Lectures (Extract Research Database)

Rating the Certainty of Evidence. Workshop on Cost Conscious Care.

European Association of Neurology, 30/06/2023

Targeted Immune Modulators for Ulcerative Colitis and Crohn’s Disease

DERP Governance Call, 06/04/2023

Prädiktoren von falsch ausgeschlossenen Studien bei der Literaturdurchsicht von systematischen Reviews: ein systematischer Review und eine Methodenstudie

22. Jahrestagung EbM-Kongress 2021, 25/02/2021

Increased risks of false-positive or false-negative findings are common in outcomes graded as high certainty of evidence

25th Cochrane Colloquium Edinburgh, Großbritannien, 18/09/2018

Wie interpretieren Autoren und Nutzer von Systematischen Reviews unterschiedliche Kategorien der Qualität der Evidenz (nach GRADE) in Bezug auf die Zuverlässigkeit von Forschungsergebnissen?

16. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin, vom 13. – 14. März 2015 in Berlin, Deutschland., 13/03/2015

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