Pharmacological Versus Non-Pharmacological Interventions for the Treatment of Major Depressive Disorder


A systematic review to support clinical practice guidelines on the pharmacological versus non-pharmacological treatments of major depressive disorder (MDD). The systematic review is structured in two parts: Part 1: Update of the 2015 Agency for Healthcare Research and Quality (AHRQ) report on pharmacological versus non-pharmacological treatments.[1] Conduct of two rapid reviews on values and preferences of patients with MDD and cost effectiveness of MDD treatments. Part 2: Additional literature searches to build a network meta-analyses model and conduct network meta-analyses of pharmacological versus non-pharmacological treatments.


Duration 10/06/2020 - 31/03/2022
Funding andere internationale Organisationen

Department for Evidence-based Medicine and Evaluation

Principle investigator for the project (Danube University Krems) Univ.-Prof. Dr. Gerald Gartlehner, MPH
Project members Lisa Affengruber, MSc Andrea Chapman, MA BSc Dr. Andreea Dobrescu Emma Persad, BSc Mag. Ana Toromanova Dr. Gernot Wagner
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