A systematic review to support clinical practice guidelines on the pharmacological versus non-pharmacological treatments of major depressive disorder (MDD). The systematic review is structured in two parts: Part 1: Update of the 2015 Agency for Healthcare Research and Quality (AHRQ) report on pharmacological versus non-pharmacological treatments.[1] Conduct of two rapid reviews on values and preferences of patients with MDD and cost effectiveness of MDD treatments. Part 2: Additional literature searches to build a network meta-analyses model and conduct network meta-analyses of pharmacological versus non-pharmacological treatments.


Duration 10/06/2020 - 31/03/2022
Funding andere internationale Organisationen

Department for Evidence-based Medicine and Evaluation

Principle investigator for the project (University for Continuing Education Krems) Univ.-Prof. Dr. Gerald Gartlehner, MPH
Project members Lisa Affengruber, MSc Andrea Chapman, MA BSc BA Dr. Andreea Dobrescu Dr. Emma Persad Mag. Ana Toromanova Dr. Gernot Wagner


Nonpharmacological Versus Pharmacological Treatments for Adult Patients with Major Depressive Disorder

ACP CGC Findings Presentation: Depression SR and NMA, 26/01/2022

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