
Alexander Otahal, PhD MSc
- alexander.otahal@donau-uni.ac.at
- +43 2732 893-5415
- To contact form
- Campus Krems, Tract C, 3rd Floor, 3.14
- University for Continuing Education Krems
- Center for Regenerative Medicine
- Dr.-Karl-Dorrek-Straße 30
- 3500 Krems
- Austria
Projects (Extract Research Database)
Running projects
Duration: 01/01/2022–31/12/2024
Principle investigator for the project (University for Continuing Education Krems): Alexander Otahal
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Completed projects
The Role of microvesicles from blood derived products in osteoarthritis
Duration: 01/01/2018–29/02/2020
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Technologieförderung NÖ
Publications (Extract Research Database)
Otahal, A.; De Luna, A.; Mobasheri, A.; Nehrer, S. (2023). Extracellular Vesicle Isolation and Characterization for Applications in Cartilage Tissue Engineering and Osteoarthritis Therapy. In: Humana Press, Cartilage Tissue Engineering: 123-140, Springer Protocols, United States of America
Otahal, A.; Kramer, K.; Kuten-Pella, O.; Moser, L.; Neubauer, M.; Lacza,Z.; Nehrer, S.; De Luna, A. (2021). Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation Model. Int J Mol Sci., 22(13): 7224
Otahal, A.; Kuten-Pella, O.; Kramer, K.; Neubauer, M.; Lacza, Z.; Nehrer, S.; De Luna, A. (2021). Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products. Sci Rep., 12;11(1): 5823
De Luna, A.; Otahal, A.; Nehrer, S. (2020). Mesenchymal Stromal Cell-Derived Extracellular Vesicles - Silver Linings for Cartilage Regeneration? Frontiers in Cell and Developmental Biology, 8:593386: 10.3389/fcell.2020.593386
Otahal, A.; Kramer, K.; Kuten-Pella, O.; Weiss, R.; Stotter, C.; Lacza, Z.; Weber, V.; Nehrer, S.; De Luna, A. (2020). Characterization and chondroprotective effects of extracellular vesicles from plasma- and serum-based autologous blood-derived products for osteoarthritis therapy. Front Bioeng Biotechnol, Sep 25: 584050
Lectures (Extract Research Database)
Extracellular vesicles in blood derived products
ICRS Word Congress, 12/01/2023
Polybrene enhances uptake of extracellular vesicles derived from Hoffa mesenchymal stromal cells into primary osteoarthritic chondrocytes
Small New World Joint Meeting of ASEV & GSEV, 29/10/2022
Extracellular vesicles from blood derived products for cartilage repair
ASEV/GSEV Joint Meeting, 28/10/2022
Functional repertoire of EV-associated miRNA profiles from blood-derived products
48th Annual ESAO Congress, 10/09/2022
Extracellular Vesicles in Blood-Derived Products for Cartilage Repair? - a status report
Annual Meeting of the Austrian Cluster of Tissue Regeneration, 27/04/2022
Extracellular Vesicles in Blood-Derived Products for Cartilage Repair
ICRS Word Congress, 14/04/2022
Association of regenerative capacity of blood EVs on primary osteoarthritic chondrocytes with EV associated miRNAs
ICRS 2022 World Congress Berlin, 14/04/2022
Extracellular vesicle-associated miRNA cargo could explain regenerative capacities of blood-derived extracellular vesicles on primary osteoarthritic chondrocytes
OARSI 2022 World Congress, 08/04/2022
Chondroprotective and anti-inflammatory effects mediated by extracellular vesicles from plasma- and serumbased blood-derived products for osteoarthritis therapy
6th world congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS2021), 17/11/2021
Regenerative capacity of blood-derived EVs on primary osteoarthritic chondrocytes coincides with the EVassociated miRNA functional repertoire
Austrian Society for Extracellular Vesicles Young Scientist Meeting, 15/10/2021