Stefan Nehrer

Univ.-Prof. Dr. Stefan Nehrer, MSc

Dean - Faculty of Health and Medicine

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Projects (Extract Research Database)

Running projects

Assessing clinically relevant biomechanical biomarkers in the field to predict physical functioning and health in patients with knee osteoarthritis: a nation-wide citizen science approach

Duration: 01/10/2024–30/09/2027
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

Nutrition and movement for self-efficacy in osteoarthritis

Duration: 01/04/2022–31/03/2026
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

Artificial intelligence in orthopedic radiography analysis

Duration: 01/03/2022–31/12/2025
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

Assessing the viability of additive manufacturing for partial replacement technologies - PrintPartialImplant

Duration: 01/01/2022–31/12/2024
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

Minced Cartilage in Regenerative Medicine

Duration: 01/08/2021–31/12/2025
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Unternehmen

Completed projects

Tribology Intelligence - Customized Tribology for Industrial Innovations

Duration: 01/04/2020–31/03/2024
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: FFG

Developmental tissue engineering model of endochondral ossification for bone regeneration

Duration: 01/01/2018–31/12/2021
Principle investigator for the project (University for Continuing Education Krems): Vivek Jeyakumar
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB

Motor Learning in Knee Osteoarthritis Therapy - A new Rehabilitation Approach

Duration: 01/01/2019–31/12/2021
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB

hypACT next

Duration: 01/01/2020–31/12/2021
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)

Treatment of OA using glucocorticoids and hyaluronic acid

Duration: 01/09/2019–31/08/2021
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Unternehmen

Tribocorrosion

Duration: 01/01/2017–30/06/2020
Principle investigator for the project (University for Continuing Education Krems): Christoph Stotter
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB

The Role of microvesicles from blood derived products in osteoarthritis

Duration: 01/01/2018–29/02/2020
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Technologieförderung NÖ

Establishment of an in vitro osteoarthritis model

Duration: 01/01/2016–30/06/2019
Principle investigator for the project (University for Continuing Education Krems): Christoph Bauer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB

SPRF Plus

Duration: 01/01/2018–31/12/2018
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Sonstige
Program: FFG

B1: Computersimulationsmodelle zur Osteoporose Früherkennung

Duration: 01/12/2015–30/11/2018
Principle investigator for the project (University for Continuing Education Krems): Tobias Haftner
Funding: FFG
Program: FFG (Bridge)

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Publications (Extract Research Database)

Fischer, J.; Pasztorek, M.; Gossy, N.; Otahal, A.; De Luna, A.; Nehrer, S.; Rosser, J. (2025). Stem cell modelling of osteoarthritis using an organ-on-a-chip approach. Inflamm Regen., 45(1):32: doi: 10.1186/s41232-025-00381-6.

Fritz, J.; Moser, A.-C.; Otahal, A.; Kramer, K.; Casurovic, S.; Teuschl-Woller, A. H.; Nehrer, S. (2025). Hydrostatic Pressure Enhances Chondrogenic Differentiation of Mesenchymal Stem Cells in Silk Fibroin-Based 3D Bioprinted Hydrogels. Biomacromolecules, -: https://doi.org/10.1021/acs.biomac.5c00048

Fritz, J.; Moser, A.-C.; Otahal, A.; Redl, H.; Teuschl-Woller, A. H.; Schneider, K. H., Nehrer, S. Andreas H. Teuschl-Woller, Karl H. Schneider, and Stefan Nehrer (2025). Silk Fibroin-Based Hydrogels Supplemented with Decellularized Extracellular Matrix and Gelatin Facilitate 3D Bioprinting for Meniscus Tissue Engineering. Macromolecular Bioscience, 2400515: https://doi.org/10.1002/mabi.202400515

Gulova, S.; Otahal, A.; Kramer, K.; Rothammer, M.; Lacza, Z.; Harvanova, D.; Nehrer, S.; De Luna, A. (2025). Extracellular vesicles from primed Hoffa's fat pad mesenchymal stem/stromal cells in osteoarthritis therapy: effects on cells critical to osteoarthritis progression. Stem Cell Res The., 16(1):578: doi: 10.1186/s13287-025-04679-7.

Moser, AC.; Fritz, J.; Otahal, A.; Kesselring, A.; Schüssler, F.; Eisner, P.; Schneider, K. H.: Teuschl, A. H.; Reissig, L.F.; Zopf, L.; Nehrer, S. (2025). Freeze drying and Lugol staining of human menisci reveal circumferential fibre volumes to guide meniscus implant design and virtual simulation. Sci Rep., 15:22798: doi: 10.1038/s41598-025-05004-1.

Moser, Anna-Christina; Fritz, Jennifer; Kesselring, Andreas; Schüssler, Florian; Otahal, Alexander; Nehrer, Stefan (2025). Biomechanical testing of virtual meniscus implants made from a bi-phasic silk fibroin-based hydrogel and polyurethane via finite element analysis. Journal of the Mechanical Behavior of Biomedical Materials, 162: 106830

Moser, L.B.; Fickert, S.; Pitzek, S.; Bauer, C.; Neubauer, M.; Dammerer, D.; Zantop, T.; Landgraeber, S.; Nehrer, S. (2025). Minced cartilage for focal cartilage defects-A comprehensive systematic review of surgical techniques in clinical studies, animal studies and basic research studies. Knee Surgery, Sports Traumatology, Arthroscopy (KSSTA), 3: 1-21

Nothnagel, RM.; Bauer, C.; Vukonic, L.; Váradi, T., Franek, F.; Nehrer, S.; Ripoll, MR. (2025). Comparative in vitro study of chondrocyte viability and gene expression in wrought and additive manufactured CoCrMo sliding against articular cartilage. J Mech Behav Biomed Mater., Volume 168: doi: 10.1016/j.jmbbm.2025.107024

Váradi, T.; Nothnagel, R.M.; Vukonic, L.; Bauer, C.; Franek, F.; Berger, L.M.; Nehrer, S.; Ripoll, M.R. (2025). Laser deposited AISI 316L reinforced with fine grained titanium carbonitride: Tribocorrosion performance compared to CoCrMo and friction behaviour against articular cartilage. Wear, online: 1-15

Chen, K.; Stotter, C.; Lepenik, C.; Klestil, T.; Salzlechner, C.; Nehrer, S.; (2024). Frontal plane mechanical leg alignment estimation from knee x-rays using deep learning. Osteoarthr Cartil Open, 2024 Nov 30;7(1):100551: 10.1016/j.ocarto.2024.100551

Chen, K.; Stotter, Ch.; Klestil, T.; Mitterer, J.; Lepenik, Ch.; Nehrer, S. (2024). Fully Automated Measurement of Cobb Angles in Coronal Plane Spine Radiographs. J. Clin Med, 2024, 13(14), 4122: https://doi.org/10.3390/jcm13144122

Hobbi, P.; Rasoulian, F.; Okoro, O.V.; Nie, L.; Nehrer, S.; Shavandi, A. (2024). Phloridzin functionalized gelatin-based scaffold for bone tissue engineering. Int J Biol Macromol., Volume 279, Part 4: https://doi.org/10.1016/j.ijbiomac.2024.135224

Höld, E.; Chmelar, S.; Aubram, T.; Leitner, G.; Nehrer, S.; Neubauer, O.; Wagner, K.-H.; Wondrasch, B. (2024). Nutrition and movement to improve quality of life in patients with knee osteoarthritis: the NUMOQUA study protocol for a randomised controlled tria. Trials, 25(1): 10.1186/s13063-024-08048-2

Kon, E.; de Girolamo, L.; Laver, L.; Andriolo L.; Andia, I.; Bastos, R.; Beaufils P.; Biant, L.; Bøe, B.; Boffa, A.; Cugat, R.; Di Martino, A.; Erggelet, C.; Iosifidis, M.; Kocaoglu, B.; Magalon, J.; Marinescu, R.; Nehrer, S.; Niemeyer, P.; Ostojic, M.; Piontek, T.; Sánchez, M.; Sas, C.; Skarpas, G.; Tischer, T.; Vonk, L.; Filardo, G. (2024). Platelet-rich plasma injections for the management of knee osteoarthritis: The ESSKA-ICRS consensus. Recommendations using the RAND/UCLA appropriateness method for different clinical scenarios. Knee Surg Sports Traumatol Arthrosc., Volume32, Issue11: 2938-2949

Kühnel, H.; Pasztorek, M.; Kuten-Pella, O.; Kramer, K.; Bauer, C.; Lacza, L.; Nehrer, S. (2024). Effects of Blood-Derived Products on Cellular Senescence and Inflammatory Re-sponse: A Study on Skin Rejuvenation. Curr. Issues Mol. Biol., Volume 46/ Issue 3: 1865–1885

Nothnagel, R.M.; Vukonic, L.; Bauer, C.; Váradi, T.; Linhardt, P.; Franek, F.; Nehrer, S.; Ripoll, M.R. (2024). Tribocorrosion Performance and Cytotoxicity of Additive Manufactured CoCrMo: A Benchmark Against Wrought CoCrMo. Journal of Bio- and Tribo-Corrosion, Nov: https://doi.org/10.1007/s40735-024-00920-7

Otahal, A.; Kramer, K.; Neubauer, M.; Gulová, S.; Lacza, Z.; Nehrer, S.; De Luna, A. (2024). Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production. Stem Cell Research and Therapy, 15: https://doi.org/10.1186/s13287-024-03681-9

Otahal, A.; Neubauer, M.; Nehrer, S. (2024). Blood Products and Stem Cells in Osteoarthritis Therapy. Z Orthop Unfall, 162(05): 533-548

Pasztorek, M.; Fischer, J.; Otahal, A.; de Luna, A.; Nehrer, S.; Rosser, J. (2024). Exploring Osteoarthritis Dynamics: Patient-Specific Cartilage Samples in an Organ-on-a-Chip Model. Cartilage, Sept: 10

Pawelczyk, J.; Kraus, M.; Eckl, L.; Nehrer, S.; Aurich, M.; Izadpanah, K.; Siebenlist, S.; Rupp, M.-C. (2024). Attitude of aspiring orthopaedic surgeons towards artificial intelligence: a multinational cross-sectional survey study. Arch Orthop Trauma Surg., Volume 144: 3541–3552

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Lectures (Extract Research Database)

Möglichkeiten von KI in der radiologischen Diagnostik

GOTS Digital Health Solution Expert Forum - Neue Technologien in der (Sport-)Orthopädie, 12/12/2024

Blutprodukte - PRP und CO, wie funktioniert das?

Sportärztewoche, 06/12/2024

Sinn und Unsinn von Lokalanästhetika im Sport – Wiss. Aspekte

DOSB-Tagung „Sportmedizin im Spitzensport 2024, 29/11/2024

Educational future in sports orthopedics

8th The International Sportmedica Congress, 22/11/2024

Knochen & Knorpel – eine untrennbare Einheit

Jahrestagung BVdO zum Thema Osteoporose, 16/11/2024

OP degenerierten Schäden – Knie

Orthopädisch-Traumatologisch-Physikalischer Grundkurs II, 09/11/2024

Update Knorpelchirurgie

Update Sportmedizin - Aktuelle Themen in der Sportmedizin, 08/11/2024

Impulsvortrag Forschung in der Sportmedizin

Update Sportmedizin - Aktuelle Themen in der Sportmedizin, 08/11/2024

Anwendung KI in der Radiologie

AGAnywhere Monthly - #035: Wie KI und VR den klinischen Alltag verändern, 05/11/2024

Keynote Lecture

VI. MuSkITYR Symposium, 04/11/2024

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