Assoz. Prof. Mag. Andrea De Luna, PhD
- andrea.de-luna@donau-uni.ac.at
- +43 2732 893-5504
- To contact form
- Campus Krems, Tract C, 3rd Floor, C 3.14
- University for Continuing Education Krems
- Center for Regenerative Medicine
- Dr.-Karl-Dorrek-Straße 30
- 3500 Krems
- Austria
Projects (Extract Research Database)
Running projects
Duration: 01/10/2024–31/03/2028
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: FWF
Duration: 01/06/2024–31/05/2027
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Completed projects
Extracellular vesicles from Hoffa´s fat pad- a new strategy for cartilage regeneration
Duration: 01/03/2020–28/02/2023
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB
The Role of microvesicles from blood derived products in osteoarthritis
Duration: 01/01/2018–29/02/2020
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Technologieförderung NÖ
Durchführbarkeitsstudie des Serumisolators hypACT
Duration: 02/05/2017–31/05/2017
Principle investigator for the project (University for Continuing Education Krems): Andrea De Luna
Funding: Unternehmen
Program: ---
Identification of novel treatment options for osteoarthritis
Duration: 05/11/2012–30/04/2016
Principle investigator for the project (University for Continuing Education Krems): Stefan Nehrer
Funding: Bundesländer (inkl. deren Stiftungen und Einrichtungen)
Program: Life Science Call NFB
Publications (Extract Research Database)
Otahal, A.; Kramer, K.; Neubauer, M.; Gulová, S.; Lacza, Z.; Nehrer, S.; De Luna, A. (2024). Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production. Stem Cell Research and Therapy, 15: https://doi.org/10.1186/s13287-024-03681-9
Pasztorek, M.; Fischer, J.; Otahal, A.; de Luna, A.; Nehrer, S.; Rosser, J. (2024). Exploring Osteoarthritis Dynamics: Patient-Specific Cartilage Samples in an Organ-on-a-Chip Model. Cartilage, Sept: 10
Neubauer, M.; Otahal, A.; Kuten, S.; Sherman, S.L.; Moser, L.; Kramer K.; DeLuna, A.; Neugebauer, J.; Dammerer, D.; Muellner, T.; Nehrer, S. (2023). Infra-patellar fat pad-derived mesenchymal stem cells maintain their chondrogenic dif-ferentiation potential after arthroscopic harvest with blood-product supplementation. Int Orthop., 30: doi: 10.1007/s00264-023-05930-7
Otahal, A.; De Luna, A.; Mobasheri, A.; Nehrer, S. (2023). Extracellular Vesicle Isolation and Characterization for Applications in Cartilage Tissue Engineering and Osteoarthritis Therapy. In: Humana Press, Cartilage Tissue Engineering: 123-140, Springer Protocols, United States of America
Otahal, A.; Tischer, T.; De Luna, A.; Nehrer, S. (2023). Plättchenreiches Plasma und andere Blutprodukte – neue Forschungsaspekte zur Wirkung von Blutderivaten und klinische Ergebnisse bei Gonarthrose. Knie Journal, 5(3): 142–149, Springer
Kuten-Pella, O.; De Luna, A.; Kramer, K.; Neubauer, M.; Nehrer, S.; Lacza, Z. (2021). Regenerative Potential of Blood-Derived Products in 3D Osteoarthritic Chondrocyte Culture System. Curr Issues Mol Biol, 43(2): 665-675
Olmos Calvo, I.; Kuten-Pella, O.; Kramer, K.; Madár, À.; Takács, S.; Kardos, D.; Simon, D.; Erdö-Bonyár, S.; Berki, T.; De Luna, A.; Nehrer, S.; Lacza Z. (2021). Optimization of Lyophilized Hyperacute Serum (HAS) as a Regenerative Therapeutic in Osteoarthritis. Int J Mol Sci, 22 (14): 7496
Otahal, A.; Kramer, K.; Kuten-Pella, O.; Moser, L.; Neubauer, M.; Lacza,Z.; Nehrer, S.; De Luna, A. (2021). Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation Model. Int J Mol Sci., 22(13): 7224
Otahal, A.; Kuten-Pella, O.; Kramer, K.; Neubauer, M.; Lacza, Z.; Nehrer, S.; De Luna, A. (2021). Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products. Sci Rep., 12;11(1): 5823
De Luna, A.; Otahal, A.; Nehrer, S. (2020). Mesenchymal Stromal Cell-Derived Extracellular Vesicles - Silver Linings for Cartilage Regeneration? Frontiers in Cell and Developmental Biology, 8:593386: 10.3389/fcell.2020.593386
Otahal, A.; Kramer, K.; Kuten-Pella, O.; Weiss, R.; Stotter, C.; Lacza, Z.; Weber, V.; Nehrer, S.; De Luna, A. (2020). Characterization and chondroprotective effects of extracellular vesicles from plasma- and serum-based autologous blood-derived products for osteoarthritis therapy. Front Bioeng Biotechnol, Sep 25: 584050
Kuten, O.; Simon, M.; Hornyák, I.; De Luna-Preitschopf, A.; Nehrer, S.; Lacza, Z. (2018). The Effects of Hyperacute Serum on Adipogenesis and Cell Proliferation of Mesenchymal Stromal Cells. Tissue Engineering Part A, Vol. 24, No. 11-12: doi: 10.1089/ten.TEA.2017.0384
De Luna-Preitschopf, A.; Zwickl, H.; Nehrer, S.; Hengstschläger, M.; Mikula, M. (2017). Rapamycin Maintains the Chondrocytic Phenotype and Interferes with Inflammatory Cytokine Induced Processes. International Journal of Molecular Sciences, 18(7): doi:10.3390/ijms18071494
Preitschopf, A.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Zwickl, H.; Rosner, M.; Joó, J.G.; Nehrer, S; Hengstschläger, M; Mikula, M. (2016). Rapamycin-Induced Hypoxia Inducible Factor 2A Is Essential for Chondrogenic Differentiation of Amniotic Fluid Stem Cells. Stem Cells Translational Medicine: 580-90
Schörghofer, D.; Kinslechner, K.; Preitschopf, A.; Schütz, B.; Röhrl, C.; Hengstschläger, M.; Stangl, H.; Mikula, M. (2015). The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence . Reprod Biol Endocrinol, Vol. 13, No. 88
Üstün, S.; Lassnig, C.; Preitschopf, A.; Mikula, M.; Müller, M.; Hengstschläger, M.; Weichhart, T. (2015). Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models. Transplantation Immunology: 45-50
Üstün, S.; Lassnig, C.; Preitschopf, A.; Mikula, M.; Müller, M.; Hengstschläger, M.; Weichhart, T. (2015). Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models. Transpl Immunol.
Preitschopf, A.; Zwickl, H.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Rosner, M.; Joo, G.J.; Hengstschläger, M.; Nehrer, S.; Mikula, M. (2015). Rapamycin enhances Sox9 Expression during Chondrogenic Differentiation of Amniotic Fluid Stem Cells. Tissue Engineering Part A, September 2015, Volume 21, Supplement 1: 192
Preitschopf, A.; Zwickl, H.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Rosner, M.; Joó, J.; Hengstschläger, M.; Nehrer, S.; Mikula, M. (2015). Rapamycin enhances SOX9 expression during chondrogenic differentiation of amniotic fluid stem cells. Tissue Engineering Part A: 192-93
Preitschopf, A.; Li, K.; Schörghofer, D.; Kinslechner, K.; Schütz, B.; Thi Thanh Pham, H.; Rosner, M.; Joo, G.; Röhrl, C.; Weichhart, T.; Stangl, H.; Lubec, G.; Hengstschläger, M.; Mikula, M. (2014). mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression. Plos One
Lectures (Extract Research Database)
Extracellular vesicles from Hoffa Fat Pad derived MSC - silver linings for cartilage repair?
Jahrestagung des Vienna Center for Engineering in Medicine, 13/12/2023
Extracellular vesicles from Hoffa Fat Pad derived mesenchymal stem cells – friends or foe?
Webinar of the Italian Society of Stem Cells, 04/07/2023
Extracellular vesicles from Hoffa Fat Pad MSCs favor the osteoarthritic phenotype of chondrocytes
Annual Meeting of the Austrian Cluster of Tissue Regeneration, 03/05/2023
Extracellular vesicles in blood derived products
ICRS World Congress, 12/04/2023
Isolation and culture of Hoffa-derived adipose MSCs for extracellular vesicle production in a vertical wheel bioreactorÖGMBT W
ÖGMBT Workshop „Advanced Cell Culture Technologies", 17/03/2023
Extracellular vesicles from blood derived products for cartilage repair
ASEV/GSEV Joint Meeting, 28/10/2022
Extracellular Vesicles in Blood-Derived Products for Cartilage Repair? - a status report
Annual Meeting of the Austrian Cluster of Tissue Regeneration, 27/04/2022
Extracellular Vesicles in Blood-Derived Products for Cartilage Repair
ICRS World Congress, 14/04/2022
Effects of extracellular vesicles from blood derivatives on osteoarthritic chondrocytes
ASEV/GSEV Joint Meeting, Freising, Deutschland, 28/11/2019
Anti-coagulation influences properties of extracellular vesicles isolated from autologous blood derived products used for cartilage repair
World Congress of the International cartilage repair and joint preservation society, Vancouver, Kanada, 08/10/2019